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Section Clinical Research

Delay And Treatment of Infectious Mononucleosis in Children

Vol. 10 No. 2 (2025): December:

Mahamadzhonov Islombek Abdurasul Ugli (1)

(1) Research Institute of Virology of the Republican Specialized Scientific and Practical Medical Center, Uzbekistan
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Abstract:

General Background: Infectious mononucleosis (IM) caused by Epstein–Barr virus (EBV) is a common childhood infection that can lead to complications when diagnosis and treatment are delayed. Specific Background: Pediatric IM often shows atypical symptoms resembling other viral illnesses, causing frequent diagnostic delays. Knowledge Gap: There is limited evidence on how such delays affect disease severity and recovery in children. Aims: This study examined the relationship between diagnostic and treatment delays and clinical outcomes in pediatric IM. Results: Children diagnosed more than 10 days after symptom onset had longer recovery, more hepatic and lymphoid complications, and higher inflammation than those diagnosed early. Novelty: The study reveals a clear link between diagnostic delay and poorer outcomes in pediatric EBV infections. Implications: Early diagnosis and standardized management are essential to prevent complications and improve recovery in infected children.
Highlight :




  • Delay in diagnosis leads to prolonged illness and higher complication rates in children.




  • Early diagnosis and treatment improve recovery and reduce systemic inflammation.




  • Highlights the need for standardized pediatric diagnostic and treatment guidelines




Keywords : Infectious mononucleosis, Epstein-Barr virus, diagnostic delay, pediatric infection, early treatment

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