Academia Open
Vol 10 No 1 (2025): June (In Progress)
Microbiology

Antibacterial activity of Fe2O3/MgO Nanoparticles against Escherichia coli isolated from contaminated Water
Aktivitas Antibakteri Nanopartikel Fe2O3/MgO terhadap Escherichia coli yang diisolasi dari Air yang terkontaminasi


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  • Ali A. Fayyadh*,
  • Jawad N. K. Makassees ,
  • Ali K. Hattab
Ali A. Fayyadh
Ministry of Education, General Directorate of Wasit Education, Wasit, Iraq *
Jawad N. K. Makassees
Ministry of Education, General Directorate of Wasit Education, Wasit, Iraq
Ali K. Hattab
Department of Physics, College of Science, University of Wasit, Wasit, Iraq

(*) Corresponding Author
Picture in here are illustration from public domain image or provided by the author, as part of their works
DOI: https://doi.org/10.21070/acopen.10.2025.10753
Published March 11, 2025
Keywords
  • Fe₂O₃ nanoparticles,
  • MgO nanoparticles,
  • antibacterial activity,
  • green synthesis,
  • water treatment
How to Cite
Fayyadh, A. A., Makassees , J. N. K., & Hattab, A. K. (2025). Antibacterial activity of Fe2O3/MgO Nanoparticles against Escherichia coli isolated from contaminated Water. Academia Open, 10(1), 10.21070/acopen.10.2025.10753. https://doi.org/10.21070/acopen.10.2025.10753

Copyright (c) 2025 Ali A. Fayyadh, Jawad N. K. Makassees , Ali K. Hattab

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

General Background: Water contamination by pathogenic bacteria, particularly Escherichia coli, poses serious public health risks, necessitating the development of effective antibacterial agents. Specific Background: Nanoparticles synthesized via green chemistry offer an environmentally sustainable alternative for bacterial control, with metal oxide nanoparticles demonstrating promising antimicrobial properties. Knowledge Gap: Despite extensive research on metal oxide nanoparticles, comparative studies on Fe₂O₃ and MgO nanoparticles synthesized from Allium sativum extract remain limited, particularly regarding their antibacterial efficacy against E. coli in contaminated water. Aims: This study investigates the antibacterial activity and characterization of Fe₂O₃ and MgO nanoparticles synthesized via a green synthesis method using Allium sativum extract, evaluating their efficacy against E. coli isolates. Results: Characterization via X-ray Diffraction (XRD), Transmission Electron Microscopy (TEM), and Fourier Transform Infrared Spectroscopy (FTIR) confirmed the structural and morphological properties of the nanoparticles. Fe₂O₃ nanoparticles exhibited superior antibacterial activity, generating 20 mm inhibition zones compared to MgO's 12-15 mm zones, attributed to their smaller size (24.41 nm), amorphous nature, and increased surface area. Novelty: This study highlights the potential of Allium sativum-mediated Fe₂O₃ nanoparticles as a more effective antibacterial agent than MgO nanoparticles. Implications: These findings support the application of green-synthesized metal oxide nanoparticles in sustainable water treatment solutions, contributing to advancements in antimicrobial technology.

Highlights:

  1. Higher Antibacterial Efficiency – Fe₂O₃ outperforms MgO in inhibition zones.
  2. Eco-Friendly Synthesis – Allium sativum ensures green nanoparticle production.
  3. Water Treatment Potential – Effective against bacterial contamination in water.
  Keywords: Fe₂O₃ nanoparticles, MgO nanoparticles, antibacterial activity, green synthesis, water treatment
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