- Malaria,
- plague,
- tuberculosis,
- epidemiology,
- response to treatment and burden of disease
Copyright (c) 2025 Ammar AL-Karawi

This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
General Background: Infectious diseases continue to pose a significant global health challenge, with malaria, plague, and tuberculosis contributing to high morbidity and mortality rates. Globalization has further accelerated their spread across borders. Specific Background: Despite medical advancements, these diseases persist due to factors such as drug resistance, high transmission rates, and regional endemicity. Pulmonary tuberculosis, in particular, remains a major concern due to its chronic nature and multidrug resistance. Knowledge Gap: Comparative studies classifying these diseases based on severity, epidemiological impact, and treatment response remain limited, making it difficult to prioritize intervention strategies effectively. Aims: This study classifies malaria, plague, and pulmonary tuberculosis using global health data to assess their epidemiological burden and treatment response. Results: Pulmonary tuberculosis presents the greatest long-term threat due to its resistance patterns. Plague, while acutely lethal, is highly treatable with timely antibiotics. Malaria remains a significant burden but is manageable with appropriate interventions. Novelty: This study integrates statistical analyses of mortality rates, transmission dynamics, and drug resistance patterns to provide a comparative classification of these diseases. Implications: Findings emphasize the necessity of early diagnosis, targeted drug development, and strengthened surveillance to enhance global infectious disease control efforts.
Highlights:
- Infectious diseases remain a global challenge due to transmission and drug resistance.
- Tuberculosis is persistent, plague is acutely lethal, malaria burdens endemic regions.
- Targeted interventions, early diagnosis, and drug development are crucial for control.
Keywords : Malaria, plague, tuberculosis, epidemiology, response to treatment and burden of disease
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