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Evaluation of β2-microglobulin, IL17, Endostatin  levels, and some biochemical variables  in patients with Chronic kidney disease  in Kirkuk city

Evaluasi kadar β2-mikroglobulin, IL17, Endostatin, dan beberapa variabel biokimia pada pasien penyakit ginjal kronis di kota Kirkuk Section Clinical Research
Vol 10 No 1 (2025): June (In Progress):
DOI : https://doi.org/10.21070/acopen.10.2025.10566
Published : Feb 4, 2025

Zina Abdulmunem Abdulrazaaq (1), Nagham Imad Abdul Hameed (2)

(1) Department of Biology, College of Education for Women, University of Kirkuk, Iraq
(2) Kirkuk Education Directorate, Kirkuk, Iraq
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Abstract:

Chronic kidney disease is the most common disease in developed countries of the world and thus poses a major challenge to public health throughout the world ,  Method:- Samples were collected randomly from patients hospitalized in Kirkuk General Hospital, in addition to some outpatient medical clinics. 55 samples were collected for patients with chronic kidney disease CKD, whose ages were (40-75) for one year for the period (1/6/2024 to 25/10/2024) Also, 30 blood samples were collected from healthy people (as a control group) .5 ml of blood sample was collected from patients and healthy people and separated using a centrifuge to obtain the serum, after which the level of the studied variables, represented by β2-microglobulin, Interlukin-17- IL-17, Endostatin, and some biochemical variables, which included (Urea, Creatinin, Uric acid, Ferritin )Result:- This study showed a significant rise in the (Β2-MG, Endostatin,  IL-17, Urea, Creatinin, Uric acid, and ferritin  ) in patients with CKD compared to healthy subjects.


Highlights:







  1. Chronic kidney disease challenges public health worldwide.

  2. Study analyzes β2-MG, IL-17, Endostatin, and biochemical markers in CKD patients.

  3. Results show significant biomarker elevation in CKD versus healthy subjects.






 

Keywords: Chronic kidney disease,  β2-microglobulin, IL-17, Endostatin

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